KESJ: 11 May 2009

Monday, May 11, 2009

11 May 2009

Jeremy's blood counts were OK again, so he didn't need any transfusions today. Hopefully, his blood counts will be OK on Wednesday so that he can have his Day 79 bone marrow aspirate - otherwise, it will be postponed. It will take a few weeks to obtain the results of his Day 79 bone marrow aspirate, as his bone marrow sample will need to be analysed at a molecular level.

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Definitions

Acute Lymphoblastic Leukaemia (ALL) - a rapidly progressing cancer of the blood and bone marrow. ALL affects the type of developing white blood cells known as lymphocytes. It is the most common form of childhood leukaemia, and the most common type of childhood cancer. It also occurs in adults.

Blast cells - immature blood cells normally found in the bone marrow. Blast cells normally constitute up to 5% of all bone marrow cells. These cells divide and replenish all the normal blood cells in the marrow and circulating blood. Acute leukaemia is characterised by an accumulation of abnormal blast cells that take over the marrow and spill out into the blood stream.

Bone marrow transplant - the process of replacing bone marrow cells (stem cells) that are unhealthy, with stem cells that are healthy. The healthy stem cells are re-infused intravenously through the central line, after very strong chemotherapy and/or radiation to kill unhealthy stem cells. The re-infusion of healthy stem cells essentially rescues the patient from the chemotherapy and/or radiation, by enabling his or her bone marrow to start producing new blood cells.